It really is pretty simple. I actually have to do it every time I want to play KOF 98 or Real Bout 2. The laser sits all the way at the bottom end or distal end for those who know medical terms. You have to take the q-tip, and only a q-tip because you don't want to scratch the laser, and push on the back of the platform that the laser sits on. If you push hard enough, it will eventually give, and then start to move freely up and down like on a tread mill. I then move the laser to about the middle or the dyaphysis of a long bone, and pop KOF 98 or Real Bout 2 in and it loads up no problem.
I am really not sure why the laser keeps getting mis-alighned, but it is a really simple fix. Its like blowing on your carts.